Do we really know the CvLPRIT in Myocardial infarction? or just stent all lesions?

SEE PAGE 963 P rimary percutaneous coronary intervention (PCI), where available, is the clear treatment of choice for ST-segment myocardial infarction (STEMI) (1). A major controversy is whether to only treat the culprit lesion or to also treat obstructive nonculprit lesions—and when. Many interventionalists believe that treating all significant lesions would provide clinical benefit, but recent guidelines and reimbursement patterns have discouraged this (2). The PRAMI (Preventive Angioplasty in Acute Myocardial Infarction) trial addressed this question in 465 patients and found an w65% reduction in ischemic events with complete revascularization during the index procedure (3). Questions persisted after this